A final vote on Kavanaugh's confirmation could come as early as tomorrow.
A key swing vote, Sen. Susan Collins (R-Maine), voted in favor of cloture on Kavanaugh's nomination. It's unclear how she'll vote on her confirmation, though she's expected to announce her decision at 3 p.m. ET, according to CNN .
Lisa Murkowski (R-Alaska) voted no, breaking party lines. Sen. Joe Manchin (D-West Virginia) also broke party lines by voting yes.
Murkowski told reporters that she was undecided in how she would vote until she walked to the Senate floor to vote.
President Trump praised the Senate vote in a tweet on Friday morning.
"Very proud of the U.S. Senate for voting “YES” to advance the nomination of Judge Brett Kavanaugh!" he tweeted.
NBC News and the Associated Press reports that Sen. Jeff Flake, who delayed a confirmation vote for a week and called for an FBI investigation into claims of sexual assault against Kavanaugh, will vote for Kavanaugh's confirmation "unless something big changes."