CINCINNATI - Johnny Cueto shook off a cramp in the fifth inning and held the Blue Jays to one earned run over eight innings, and Todd Frazier hit a two-run homer to lead the Reds to a 4-3 victory Sunday.
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Cueto (7-5) leads the NL with a 1.86 ERA. He gave up two unearned runs and seven hits and struck out eight.
Aroldis Chapman struck out the side in the ninth for his 13th save.
The win lifted the Reds back to .500 at 37-37.
Frazier's homer broke a 2-2 tie off R.A. Dickey (6-6). Frazier has 17 homers to lead the Reds and is tied with Pittsburgh's Andrew McCutchen and Baltimore's Adam Jones for the most home runs in the month of June with seven.
Both teams lost stars due to injuries.
Brandon Phillips left in the middle of the fifth inning with a bruised right heel, and Cueto had to shake off a hamstring cramp in the bottom of the inning to stay in the game.
Phillips is considered day-to-day.
Reds manager Bryan Price said Phillips got hurt in the third inning when he swung and the bat hit his heel on the backswing.
"He did not want to come out of the game and I made that decision," Price said. "Hopefully there will be a lot of progress made between now and tomorrow's game."
Cueto cramped while running the bases after Frazier homered in the fifth. Cueto got on with a bunt single.
"When Frazier hit that ball, I went back to tag and I felt it," Cueto said through a translator. "It was just a cramp."
Toronto's Todd Lawrie sustained a broken right index finger when he was hit by a pitch in the second. The team didn't immediately announce how long the infielder would be out.
Juan Bautista left because of tightness in his left leg. The All-Star outfielder had a single and a sacrifice bunt before leaving.
"It's definitely tough," said Lawrie, who said he expects to be placed on the disabled list. "We're big pieces of the puzzle, especially (Bautista). It's tough on the team to not have all its bullets. We just have to keep on grinding.
Former Red Edwin Encarnacion led off the Toronto eighth with his 24th home run and third in the three-game series.
The Reds used Encarnacion's error at first to take a 1-0 lead in the first. With Frazier on first and two outs, Phillips was safe when Encarnacion couldn't handle third baseman Juan Francisco's throw on a chopper. Jay Bruce converted the error with an RBI single.
The Blue Jays got help from two errors to take a 2-1 lead in the third. Munenori Kawasaki reached on first baseman Joey Votto's throwing error, Melky Cabrera singled and Toronto loaded the bases on Cueto's misplay of Jose Bautista's bunt. One out later, Colby Rasmus lined a two-run single.
The Reds tied the game in the fourth on Bruce's leadoff double, Ryan Ludwick's single and Brayan Pena's run-scoring double-play grounder.
Encarnacion, who a pair of three-run homers Friday night, homered off Cueto into the left-field seats.
NOTES: Bautista was scheduled for an MRI on Monday. He left for pinch-runner Jose Reyes, who didn't start after fouling a ball off the side of his left knee on Saturday. ... Phillips left in the middle of the fifth with a bruised right heel. ... Toronto is scheduled to open a seven-game homestand with the first of three against the Yankees on Monday. ... The Reds are due to open their second 10-game road trip of the season with the first of three games against the Cubs.