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Comair announced Tuesday that the airline will layoff more than 500 employees.
Officials say the layoffs will happen once 14 of its 50-seat regional jets are taken out of service this fall.
Among the employees affected are 300 pilots and 220 flight attendants.
Comair has two flight operations centers, one at the CVG airport in Northern Kentucky and another in New York City.
The majority of the layoffs will happen in New York because that's where most of the planes will be pulled from service.
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